223P Overall survival (OS) results of phase III ARAMIS study of darolutamide (DARO) added to androgen deprivation therapy (ADT) for non-metastatic castration-resistant prostate cancer (nmCRPC)
نویسندگان
چکیده
منابع مشابه
International survey of androgen deprivation therapy (ADT) for non-metastatic prostate cancer in 19 countries
BACKGROUND Continuous androgen deprivation therapy (CADT) is commonly used for patients with non-metastatic prostate cancer as primary therapy for high-risk disease, adjuvant therapy together with radiation or for recurrence after initial local therapy. Intermittent ADT (IADT), a recently developed alternative strategy for providing ADT, is thought to potentially reduce adverse effects, but lit...
متن کاملSurvival Outcomes of Concurrent Treatment with Docetaxel and Androgen Deprivation Therapy in Metastatic Castration-Resistant Prostate Cancer
PURPOSE Docetaxel-based chemotherapy (DTX) improves overall survival (OS) of men with metastatic castration-resistant prostate cancer (mCRPC). Considering the potential existence of androgen receptors that remain active at this stage, we aimed to assess the impact of the combined use of androgen deprivation therapy (ADT) with DTX for mCRPC. MATERIALS AND METHODS We performed a single-institut...
متن کاملCost-Utility Analysis Of Enzalutamide For Patients With Chemotherapy-Naïve Metastatic Castration-Resistant Prostate Cancer (Mcrpc) After Failure Of Androgen Deprivation Therapy (Adt).
PCN248 Cost-Utility ANAlysis of ENzAlUtAmidE for PAtiENts With ChEmothErAPy-NAïvE mEtAstAtiC CAstrAtioN-rEsistANt ProstAtE CANCEr (mCrPC) AftEr fAilUrE of ANdrogEN dEPrivAtioN thErAPy (Adt) Vicente C1, Loblaw A2, North S3, Kassouf W4, Naidoo S5, Husein F6, Nakhaipour HR6 1PIVINA Consulting Inc., Mississauga, ON, Canada, 2University of Toronto, Toronto, ON, Canada, 3University of Alberta, Edmont...
متن کاملEditorial on an international survey of androgen deprivation therapy (ADT) for non-metastatic prostate cancer in 19 countries
Correspondence to Dr Cora N Sternberg, MD, FACP; cnsternberg@ corasternberg.com The widespread use of prostatic specific antigen (PSA) testing has greatly impacted on the epidemiology of prostate cancer. Patients are often discovered at an early stage and testing is also performed in patients who are too elderly or frail for local treatments such as prostatectomy or radiation therapy. Only rece...
متن کاملCancer Therapy: Clinical Phase II Study of Dasatinib in Patients with Metastatic Castration-Resistant Prostate Cancer
Purpose: Antiproliferative and antiosteoclastic activity from preclinical models show potential for dasatinib, an oral SRC and SRC family kinase inhibitor, as a targeted therapy for patients with prostate cancer. This phase II study investigated the activity of dasatinib in patients with metastatic castration-resistant prostate cancer (CRPC). Experimental Design: Chemotherapy-naive men with CRP...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2020
ISSN: 0923-7534
DOI: 10.1016/j.annonc.2020.10.443